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Table 3 Association of smoking with nasal malignancies

From: Risk factors for nasal malignancies in German men: the South-German Nasal cancer study

 

Controls (%)

Cases (%)

OR (95% CI)

All study participants

   

Reference*

986 (41.1)

135 (31.6)

1.00

Smoking (ever)

1415 (58.9)

292 (68.4)

1.60 (1.24–2.07)

Smoking (per pack-year)

1415 (58.9)

292 (68.4)

1.06 (1.05–1.07)

Pack-years (quartiles) <8.6

352 (14.7)

36 (8.4)

0.53 (0.35–1.18)

8.6 < 14.5

345 (14.4)

32 (7.5)

0.67 (0.42–1.06)

14.5 < 21.75

365 (15.2)

49 (11.5)

1.05 (0.70–1.58)

21.75+

354 (14.7)

175 (41.0)

4.11 (3.01–5.62)

Impact of quitting

   

Reference*

986 (65.0)

135 (70.6)

1.00

Duration since quitting (tertiles) <15 years

158 (10.4)

22 (11.5)

1.11 (0.69–1.79)

15–27 years

175 (11.5)

22 (11.5)

1.13 (0.73–1.75)

28+ years

199 (13.1)

12 (6.3)

0.44 (0.26–0.74)

  1. * Non-smokers.
  2. Adjustments: Year of birth, community size, educational attainment, nasal snuff package-years, years of exposure to hardwood dust, asbestos, organic solvents, use of nasal spray/nasal lavage and ever-use of insecticides in homes.