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Table 2 PIK3CA mutations and amplification in gastric cancer--multivariable models assessing tumor size, differentiation, tumor stage, lymph node metastasis and survival status (OR† and 95%CI)

From: Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer

Factors

PIK3CA mutations [OR† (95% CI)]

PIK3CA amplification [OR† (95% CI)]

Tumor size1

0.80 (0.29-2.21)

0.88 (0.50-1.54)

Differentiation2

5.53 (0.65-47.4)

1.85 (0.86-4.02)

Tumor stage3

1.19 (0.33-4.35)

0.60 (0.31-1.17)

Lymph node metastasis

1.32 (0.13-13.6)

1.44 (0.45-4.58)

Survival status4

0.41 (0.07-2.41)

3.50 (1.36-9.00)*

  1. * Significant at P < 0.05
  2. † OR: odds ratio with 95% confidence interval
  3. 1 Tumor size (≤ 3 cm; > 3 cm and ≤ 5 cm; > 5)
  4. 2 Differentiation (well or moderate; poor or no differentiation)
  5. 3 Tumor stage (I; II; III; IV)
  6. 4 Survival status (alive; dead)
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BMC Cancer

ISSN: 1471-2407

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