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Table 2 Levels of biomarkers before, 3, 6, 24 and 48 h after application of SIRT

From: Predictive and prognostic value of circulating nucleosomes and serum biomarkers in patients with metastasized colorectal cancer undergoing Selective Internal Radiation Therapy

  Reference value (95th perc. of healthy) 0 hours 3 hours 6 hours 24 hours 48 hours
   Median Median Median Median Median
   Range Range Range Range Range
Nucleo-somes [ng/mL]   190.5 197.6 237.4 758.5 596.0
  < 36 5.0-1624 34.8-2501 40.7-2064 21.7-4334 51.7-2547
CYFRA 21-1
[ng/mL]
  10.9 9.3 8.8 28.6 27.5
  < 2.2 0.8-246.0 0.9-240.0 1.1-230.0 1.0-811.0 1.5-638.0
CEA
[ng/mL]
  330.0 343.5 356.5 351.0 433.0
  < 3.4 2.0-31620 1.9-33010 1.9-16980 1.6-36120 1.6-37550
CA 19-9 [U/mL]   40.0 41.6 49.7 48.7 56.4
  < 37 2.4-11530 2.3-24400 2.2-8748 2.4-18550 2.3-17000
LDH
[U/L]
  407.0    486.5 585.0
  < 250 178.0-3068    143.0-2923 142.0-3585
CRP
[mg/dL]
  1.3    1.3 4.6
  < 0.5 0.1-20.3    1.3-21.8 0.1-16.3
CHE
[kU/L]
  7.3    6.3 5.9
  5.0-13.3 2.8-11.1    2.8-11.1 5.9-10.5
AST
[U/L]
  52.0    74.5 68.5
  < 33 24.0-190.0    15.0-339.0 19.0-317.0
ALT
[U/L]
  34.5    46.0 48.5
  < 35 15.0-268.0    14.0-178.0 13.0-136.0
Bilirubin
[mg/dL]
  0.7    1.0 1.2
  < 1.0 0.3-1.9    0.4-2.2 0.4-2.8
AP
[U/L]
  160.0    148.0 156.0
  < 135 81.0-742.0    63.0-655.0 61.0-630.0
GGT
[U/L]
  183.5    165.5 168.5
  < 38 33.0-712.0    31.0-577.0 31.0-653.0
Amylase
[U/L]
  58.0    44.0 46.5
  < 100 20.0-136.0    20.0-429.0 20.0-519.0
Lipase
[U/L]
  26.0    18.0 20.0
  < 60 3.0-263.0    3.0-585.0 3.0-495.0