Predictive and prognostic value of circulating nucleosomes and serum biomarkers in patients with metastasized colorectal cancer undergoing Selective Internal Radiation Therapy

Table 1 Characteristics of patients with colorectal cancer and liver metastases undergoing SIR therapy

	Median	Range
Age	62.6 years	35.3 - 77.9 years
Time to SIRT after primary diagnosis	25 months	6-140
	Number	Percentage (%)
Patients	49	100
Gender
Female	16	32.7
Male	33	67.3
Localisation of primary tumor
Colon	11	22.5
Sigma	22	44.0
Rectum	16	32.5
Chemotherapies before SIRT
FOLFOX	42	85.7
FOLFIRI	47	95.9
Therapy response
REM	9	18.4
SD	5	10.2
PD	35	71.4
Progression defining
liver metastases	19	54.3
extrahepatic manifestation	6	17.1
deceased	10	28.6
One year survival*
Yes	22	45.8
No	26	54.2
	Median	95% Conf. Interval
Overall survival	8.8 months	5.1-18.1