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Table 2 Treatment characteristics

From: Hypofractionated stereotactic radiotherapy of limited brain metastases: a single-centre individualized treatment approach

  Total metastases (108) Primary Range Recurrence Range
    m=52   m=56  
GTV Median (ccm) 1.0 0.1-19.0 2.0 0.1-29.2
PTV Median (ccm) 4.7 1.1-41.0 9.2 1.6-62.4
Brain volume treated with 4 Gy (V4Gy) Median (ccm) 18.4 0-55.3 16.6 0-68.7
Duration of hfSRT Median (days) 15 8-32 16 5-23
Recurrence situation WBRT dose concepts     [%]
  - 10x3 Gy 0   27 48.2
  - 15x2.5 Gy 0   11 19.7
  - 15x2 Gy 0   4 7.1
  - 20x2 Gy 0   8 14.3
  - others 0   6 10.7
   m [%] m [%]
Localization of brain metastases frontal/frontoparietal 15 28.8 13 23.2
  temporal 1 1.9 6 10.7
  parietal/occipital 13 25.0 15 26.8
  central brain 7 13.5 7 12.5
  brainstem 3 5.8 2 3.6
  cerebellum 8 15.4 11 19.6
  others 5 9.6 2 3.6
Dose concepts EQD2 (Gy) median GTV (ccm)     
10x3 Gy 33 9.29 1 1.9 3 5.4
5x4 Gy 23 4.00   0.0 3 5.4
7x4 Gy 33 4.70   0.0 11 19.6
8x4 Gy 37 2.75 2 3.8 4 7.1
9x4 Gy 42 5.56   0.0 2 3.6
10x4 Gy 47 4.50 7 13.5 2 3.6
4x5 Gy 25 4.00   0.0 1 1.8
5x5 Gy 31 2.00   0.0 5 8.9
6x5 Gy 38 1.00 10 19.2 14 25.0
7x5 Gy 44 0.87 22 42.3 4 7.1
5x6 Gy 40 0.76 10 19.2 7 12.5
total   1.46 52 100.0 56 100.0