Table 1 Patients characteristics
Total patients n=75 | |||||
|---|---|---|---|---|---|
Primary n=41 | Recurrence n=34 | ||||
Age | Median (years), range | 57.3 | 40.2-79.2 | 57.7 | 38.4-79.9 |
n | [%] | n | [%] | ||
Gender | male | 20 | 48.8 | 15 | 44.1 |
female | 21 | 51.2 | 19 | 55.9 | |
Primary tumour | Non-small cell lung cancer | 22 | 53.6 | 11 | 32.4 |
Breast cancer | 5 | 12.2 | 12 | 35.3 | |
Malignant melanoma | 6 | 14.6 | 3 | 8.8 | |
Renal cell carcinoma | 4 | 9.8 | 2 | 5.9 | |
Small cell lung cancer | 0 | 0 | 5 | 14.7 | |
Others | 4 | 9.8 | 1 | 2.9 | |
RPA-classification | 1 | 7 | 17.1 | 13 | 38.2 |
2 | 34 | 82.9 | 21 | 61.8 | |
3 | 0 | 0 | 0 | 0 | |
Extracranial tumour status | in remission | 5 | 12.2 | 11 | 32.4 |
detectable, stable disease | 10 | 24.4 | 8 | 23.5 | |
progressive | 26 | 63.4 | 15 | 44.1 | |
Metastases treated with hfSRT (patients) | 1 | 32 | 78.0 | 19 | 55.9 |
2 | 7 | 17.1 | 9 | 26.5 | |
3 | 2 | 4.9 | 5 | 14.7 | |
4 | 0 | 0 | 1 | 2.9 | |
Time between diagnosis of primary tumour and brain metastasis | Median (months), range | 12.5 | 0-166.4 | 12.3 | 0-337.7 |
Time between diagnosis of brain metastasis and start of hfSRT | Median (month), range | 1.4 | 0.2-39.9 | 11.4 | 0.5-37.9 |
Intervall between WBRT and start of hfSRT | Median (month), range | 0 | 0 | 12.7 | 0.5-28.8 |