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Table 2 DNA Repair Capacity (DRC) of women with breast cancer (BC) and women without BC by age group

From: The association of DNA Repair with breast cancer risk in women. A comparative observational study

Variable

Women with BC n (mean DRC)

Women without BC n (mean DRC)

Crude OR1

Adjusted OR2

P value

 

(95% CI)

(95% CI)

 

  Decreasing DRC (continuous)*

285 (2.41)

539 (6.13)

2.2 (1.9, 2.4)

2.3 (2.0, 2.6)

< 0.001

  DRC

  Low (< 4.3%)

246

168

13.9 (9.4, 20.4)

15.1 (10.0, 22.9)

< 0.001

  High (≥ 4.3%)

39

371

   

  DRC levels3

  Low (0.0-3.0%)

213

66

54.6 (30.3, 98.5)

60.6 (32.1, 114.6)

< 0.001

  Medium (3.01-5.8%)

57

219

4.4 (2.4, 8.0)

13.0 (8.5, 20.0)

< 0.001

  High (≥5.81%)

15

254

Referent

Referent

 
  1. *Mean values presented in parenthesis.
  2. Comparisons were measured with the crude1 and the adjusted2 multiple logistic regression odds ratio (OR) in the total sample divided by patients and women without breast cancer.
  3. 1Crude or unadjusted analysis: The analysis is carried out without taking into consideration potential confounders.
  4. 2Adjusted analysis: The analysis is carried out adjusting for the potential effect of all confounding variables simultaneously by using logistic regression model.
  5. 3Chi-Square for linear trend = 233.6, p< 0.001.
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BMC Cancer

ISSN: 1471-2407

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