Table 4 Impact of patient characteristics and treatment modality on the cause of death (n = 40)
From: Brain metastases from hepatocellular carcinoma: clinical features and prognostic factors
| Â | Cause of death | Â | |
|---|---|---|---|
Variables | Neurological (n = 23) | Systemic (n = 17) | P-value |
Lung metastasis | Â | 0.026 | |
   Yes | 14 | 16 |  |
   No | 9 | 1 |  |
Extracranial metastasis | Â | 0.107 | |
   Yes | 16 | 16 |  |
   No | 7 | 1 |  |
Brain hemorrhage | 0.538 | ||
   Yes | 12 | 7 |  |
   No | 11 | 10 |  |
Number of BM | Â | Â | 0.337 |
   1 | 15 | 8 |  |
   ≥ 2 | 8 | 9 |  |
RPA class | Â | Â | < 0.0001 |
   I or II | 8 | 16 |  |
   III | 15 | 1 |  |
Treatment for BM | Â | 0.024 | |
   Steroid only | 17 | 6 |  |
   Surgery or WBRT and/or SRS | 6 | 11 |  |