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A closed-tube methylation-sensitive high resolution melting assay (MS-HRMA) for the semi-quantitative determination of CST6 promoter methylation in clinical samples

  • Lampros Dimitrakopoulos1,
  • Panagiotis A Vorkas1, 3,
  • Vasilis Georgoulias2 and
  • Evi S Lianidou1Email author
BMC Cancer201212:486

Received: 25 April 2012

Accepted: 23 September 2012

Published: 22 October 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
25 Apr 2012 Submitted Original manuscript
16 May 2012 Reviewed Reviewer Report - Yong-June Kim
4 Jul 2012 Reviewed Reviewer Report - Ulrich Lehmann
5 Jul 2012 Reviewed Reviewer Report - Temduang Limpaiboon
24 Aug 2012 Author responded Author comments - Evi Lianidou
Resubmission - Version 2
24 Aug 2012 Submitted Manuscript version 2
23 Sep 2012 Editorially accepted
22 Oct 2012 Article published 10.1186/1471-2407-12-486

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Laboratory of Analytical Chemistry, Department of Chemistry, University of Athens, Athens, Greece
Department of Medical Oncology, University General Hospital of Heraklion, Crete, Greece
Biomolecular Medicine, Department of Surgery and Cancer, Imperial College London, London, UK