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Figure 2 | BMC Cancer

Figure 2

From: Sorafenib modulates the radio sensitivity of hepatocellular carcinoma cells in vitro in a schedule-dependent manner

Figure 2

Clonogenic survival of human hepatocellular carcinoma cells SMMC-7721 (A, C) and BEL-7402 (B, D) after irradiation with or without sorafenib . A, B Sorafenib (15 mM) was added 30 min prior to irradiation of cells (pre-IR sorafenib). C, D. Cells were irradiated (0-10 Gy) and sorafenib was added 24 h post irradiation (post-IR sorafenib). Survival fraction (SF) was calculated by using the mean plating efficiency (PE) of untreated cells as the denominator to illustrate independent cytotoxic effects of sorafenib; linear quadratic (LQ) equation was fitted to data.

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BMC Cancer

ISSN: 1471-2407

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