Figure 6
From: Wnt5a promotes ewing sarcoma cell migration through upregulating CXCR4 expression
Involvement of JNK in Wnt5a-induced ES cell migration. (A) and (B) Expression of p-JNK and p-cJUN decreased in SK-N-MC and SK-ES-1 cells after treatment with Wnt5a shRNA or rSFRP5. (C) and (D) Level of CXCR4 mRNA in SK-N-MC and SK-ES-1 cells decreased after treatment with JNK inhibitor SP600125, *P<0.01, vs control. (E) and (F) The number of migrated SK-N-MC and SK-ES-1 cells decreased after treatment with SP600125, *P<0.01, vs control. Data are expressed as mean±SD, n=3.