Figure 5
From: Wnt5a promotes ewing sarcoma cell migration through upregulating CXCR4 expression
Inhibition of CXCR4 expression and ES cell migration by SFRP5. (A) and (B) Level of CXCR4 mRNA decreased in SK-N-MC and SK-ES-1 cells after treatment with rSFRP5 or transfection with SFRP5 expression vector, *P<0.01, vs Control. (C) and (D) The number of migrated SK-N-MC and SK-ES-1 cells decreased after treatment with rSFRP5 or transfection with SFRP5 expression vector, *P<0.01, vs Control. (E) and (F) SFRP5 was expressed in SK-N-MC and SK-ES-1 cells after treatment with pcDNA3.1 SFRP5 vector. Data are expressed as mean±SD, n=3.