Figure 4
From: Wnt5a promotes ewing sarcoma cell migration through upregulating CXCR4 expression
SFRP5 methylation in Ewing sarcoma tissues and cells. (A) SFRP5 methylation was detected in 13 of 15 ES specimens. (B) SFRP1 and SFRP2 were methylated in SK-N-MC and SK-ES-1, while SFRP5 was methylated in all of 4 ES cell lines. (C) Expression of SFRP5 protein was restored in 4 ES cells after treatment with DAC. (D) SFRP1 and SFRP2 were strongly expressed in A-673 and RD-ES, but weakly expressed in SK-ES-1, and not expressed in SK-N-MC.