Figure 5
From: Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma
Impaired phosphorylation of p38 and ERK after CD40L stimulation in SLL/CLL samples. Lymphoma patient samples and PBMCs from healthy donors where stimulated with CD40L for 15 minutes and the expression of different phospho-proteins was measured by flow cytometry as indicated. Shown is a scatter plot of MFI in the CD20+CD5+/CD20+-subset, relative to the corresponding unstimulated sample from the same individual. SLL/CLL (n = 11), MZL (n = 5) and PBMC (n = 9); * p < 0.05; Mann Whitney test.