Figure 1
From: Expression and significance of histone H3K27 demethylases in renal cell carcinoma
Real-time qRT-PCR analysis of the H3K27 demethylases UTX and JMJD3 , the H3K27 methyltransferase EZH2 and the CDK4/CDK6 inhibitor p16INK4a. Relative mRNA expression levels of UTX, JMJD3 and EZH2 were higher in RCC cancer tissues than in paired adjacent normal tissues (n = 36; all P < 0.05). The mRNA level of p16INK4a was also upregulated in cancer tissues compared to adjacent normal tissues (P < 0.001).