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Table 2 Univariate analysis of prognostic factors for OS

From: The oncoprotein and stem cell renewal factor BMI1 associates with poor clinical outcome in oesophageal cancer patients undergoing preoperative chemoradiotherapy

Covariate

 

n

Hazard ratio

95%CI

P-value for OS

Age (years)

≥70

22

1.111

0.552-2.234

0.770

 

<70

56

   

Gender

Male

65

0.312

0.096-1.016

0.023*

 

Female

13

   

Effect of CRT

Effective

56

0.191

0.098-0.370

0.0001***

 

Not effective

22

   

Lymph-node

Positive

34

2.624

1.382-4.983

0.002**

metastasis

Negative

44

   

Distant metastasis

Positive

12

3.988

2.001-7.947

0.0001***

 

Negative

66

   

Depth of tumour

T3

40

0.308

0.157-0.602

0.0001***

invasion

T4

38

   

Tumour location1

Upper

13

1.299

0.597-2.827

0.509

 

Lower

65

   

BMI1 expression

positive

24

3.347

1.775-6.313

0.0001***

 

negative

54

   
  1. 1 Upper or lower: above or below the tracheal bifurcation.
  2. *P<0.05; ** P<0.005; *** P<0.0005.