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Table 4 Objective response rate by worst skin toxicity grade

From: Skin toxicity and quality of life in patients with metastatic colorectal cancer during first-line panitumumab plus FOLFIRI treatment in a single-arm phase II study

Objective response rate, % (95% CI)

WT KRAS

MT KRAS

Overalla

Grade 0/1 (n = 16)

Grade 2+ (n = 69)

Overall (n = 85)

Grade 0/1 (n = 19)

Grade 2+ (n = 39)

Overall (n = 58)

Grade 0/1 (n = 35)

Grade 2+ (n = 117)

Overall (n = 152)

37.5 (15.2, 64.6)

60.9 (48.4, 72.4)

56.5 (45.3, 67.2)

21.0 (6.0, 45.6)

46.2 (30.1, 62.8)

37.9 (25.5, 51.6)

28.6 (14,6, 46.3)

55.6 (46.1, 64.7)

49.3 (41.2, 57.6)

  1. Objective response rate represents the proportion of patients with a best overall response of complete or partial response.
  2. aAll patients in the tumour response analysis set regardless of KRAS evaluability.
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BMC Cancer

ISSN: 1471-2407

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