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Table 4 Objective response rate by worst skin toxicity grade

From: Skin toxicity and quality of life in patients with metastatic colorectal cancer during first-line panitumumab plus FOLFIRI treatment in a single-arm phase II study

Objective response rate, % (95% CI)
WT KRAS MT KRAS Overalla
Grade 0/1 (n = 16) Grade 2+ (n = 69) Overall (n = 85) Grade 0/1 (n = 19) Grade 2+ (n = 39) Overall (n = 58) Grade 0/1 (n = 35) Grade 2+ (n = 117) Overall (n = 152)
37.5 (15.2, 64.6) 60.9 (48.4, 72.4) 56.5 (45.3, 67.2) 21.0 (6.0, 45.6) 46.2 (30.1, 62.8) 37.9 (25.5, 51.6) 28.6 (14,6, 46.3) 55.6 (46.1, 64.7) 49.3 (41.2, 57.6)
  1. Objective response rate represents the proportion of patients with a best overall response of complete or partial response.
  2. aAll patients in the tumour response analysis set regardless of KRAS evaluability.