|
Objective response rate, % (95% CI)
|
|---|
|
WT KRAS
|
MT KRAS
|
Overalla
|
|---|
|
Grade 0/1 (n = 16)
|
Grade 2+ (n = 69)
|
Overall (n = 85)
|
Grade 0/1 (n = 19)
|
Grade 2+ (n = 39)
|
Overall (n = 58)
|
Grade 0/1 (n = 35)
|
Grade 2+ (n = 117)
|
Overall (n = 152)
|
|---|
|
37.5 (15.2, 64.6)
|
60.9 (48.4, 72.4)
|
56.5 (45.3, 67.2)
|
21.0 (6.0, 45.6)
|
46.2 (30.1, 62.8)
|
37.9 (25.5, 51.6)
|
28.6 (14,6, 46.3)
|
55.6 (46.1, 64.7)
|
49.3 (41.2, 57.6)
|
- Objective response rate represents the proportion of patients with a best overall response of complete or partial response.
-
aAll patients in the tumour response analysis set regardless of KRAS evaluability.
