|
Time to first integument
toxicity, days [min, max]
|
|
Any grade
|
8.0 (7,0, 10.0)
|
10.0 (7.0, 13.0)
|
8.0 (7.0, 11.0)
|
|
[0, 155]
|
[0, 125]
|
[0, 155]
|
|
Grade ≥3
|
NE (300.0, NE)
|
NE (175.0, NE)
|
408.0 (300.0, NE)
|
| |
[6, 528]
|
[0, 389]
|
[0, 528]
|
|
Duration of integument toxicity,
days [min, max]
|
|
Any grade
|
452.0 (244.0, NE)
|
321.0 (228.0, 371.0)
|
334.0 (244.0, NE)
|
|
[14, 492]
|
[19, 445]
|
[14, 492]
|
|
Grade ≥3
|
32.0 (17.0, 43.0)
|
55.5 (25.0, 80.0)
|
36.0 (25.0, 54.0)
|
| |
[5, 322]
|
[5, 268]
|
[5, 322]
|
|
Time to resolution, days
[min, max]
|
|
Any grade
|
103.0 (55.0, NE)
|
71.0 (52.0, 86.0)
|
71.0 (59.0, 162.0)
|
|
[0, 309]
|
[5, 162]
|
[0, 309]
|
|
Grade ≥3
|
103.0 (68.0, NE)
|
86.0 (86.0, 162.0)
|
86.0 (68.0, 162.0)
|
| |
[0, 124]
|
[12, 162]
|
[0, 162]
|
