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Table 3 Univariate analyses comparing survival in patient subgroups stratified by clinicopathologic characteristics

From: Impact of modern chemotherapy on the survival of women presenting with de novo metastatic breast cancer

Characteristic Hazard ratio 95%CI P-value
Date of diagnosis    
 Period A 1.00 reference 0.10
 Period B 0.95 0.92 – 1.00  
Age (years)    
 ≤ 50 1.00 reference 0.06
 > 50 1.27 1.00 – 1.63  
Histology    
 Non-Inflammatory 1.00 reference 0.21
 Inflammatory 1.22 0.88 – 1.69  
ER Status    
 Negative 1.00 reference 0.03
 Positive 0.69 0.50 – 0.96  
PR Status    
 Negative 1.00 reference 0.17
 Positive 0.8 0.59 – 1.09  
HER2 Status    
 Negative 1.00 reference 0.08
 Positive 0.55 0.28 – 1.08  
Liver Mets    
 No 1.00 reference 0.60
 Yes 1.08 0.80 – 1.44  
Lung Mets    
 No 1.00 reference 0.10
 Yes 1.25 0.95 – 1.65  
Brain Mets    
 No 1.00 reference 0.22
 Yes 1.43 0.80 – 2.56  
Bone Mets    
 No 1.00 reference 0.06
 Yes 1.29 0.98 – 1.70  
Bone Only Mets    
 No 1.00 reference 0.23
 Yes 0.83 0.62 – 1.12  
Supraclavicular Node Mets    
 No 1.00 reference 0.56
 Yes 0.92 0.69 – 1.22  
Soft Tissue Mets    
 No 1.00 reference 0.53
 Yes 1.11 0.78 – 1.59