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Table 1 Characteristics of lung cancer cases and controls

From: Genetic polymorphisms in CYP1A1, GSTM1, GSTP1 and GSTT1metabolic genes and risk of lung cancer in Asturias

Characteristic Cases (n = 789) Controls (n = 789) pa
n (%) n (%)
Gender
  Male 697 (88.3) 697 (88.3) 1.000
  Female 92 (11.7) 92 (11.7)  
Age (yrs), median (range) 67 (33–84) 66 (30–87) 0.034
  n 789 789  
Smoking Status
  Never 51 (6.5) 222 (28.1) <0.001
  Ever 738 (93.5) 567 (71.9)  
  Former 231 (29.8) 291 (37.3) <0.001
  Current 494 (63.7) 268 (34.3)  
Pack-years b, median (range) 54 (0.65-274.5) 30.1 (0.05-170) <0.001
  n 736 559  
Family history of any cancer
  None 431 (57.2) 467 (59.9) .004
  Other cancers 237 (31.4) 262 (33.6)  
  Lung cancer 86 (11.4) 51 (6.5) 0
Worker in list A occupationc
  No 641 (81.2) 685 (86.8) 0.002
  Yes 148 (18.8) 104 (13.2)  
Histological type
  Squamous cell carcinoma 313 (39.8)   
  Adenocarcinoma 246 (31.3)   
  Small cell carcinoma 133 (16.9)   
  Large cell carcinoma 24 (3.1)   
  Non-differentiated 49 (6.2)   
  Others 9 (1.1)   
  Clinical diagnosis 13 (1.6)   
  Missing 2   
  1. a Two-sided Chi-squared test and Mann–Whitney test where appropriate.
  2. b Pack-years for ever smokers.
  3. c List A includes occupations known to be associated with lung cancer.