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Table 1 Characteristics of lung cancer cases and controls

From: Genetic polymorphisms in CYP1A1, GSTM1, GSTP1 and GSTT1metabolic genes and risk of lung cancer in Asturias

Characteristic

Cases (n = 789)

Controls (n = 789)

pa

n (%)

n (%)

Gender

  Male

697 (88.3)

697 (88.3)

1.000

  Female

92 (11.7)

92 (11.7)

 

Age (yrs), median (range)

67 (33–84)

66 (30–87)

0.034

  n

789

789

 

Smoking Status

  Never

51 (6.5)

222 (28.1)

<0.001

  Ever

738 (93.5)

567 (71.9)

 

  Former

231 (29.8)

291 (37.3)

<0.001

  Current

494 (63.7)

268 (34.3)

 

Pack-years b, median (range)

54 (0.65-274.5)

30.1 (0.05-170)

<0.001

  n

736

559

 

Family history of any cancer

  None

431 (57.2)

467 (59.9)

.004

  Other cancers

237 (31.4)

262 (33.6)

 

  Lung cancer

86 (11.4)

51 (6.5)

0

Worker in list A occupationc

  No

641 (81.2)

685 (86.8)

0.002

  Yes

148 (18.8)

104 (13.2)

 

Histological type

  Squamous cell carcinoma

313 (39.8)

  

  Adenocarcinoma

246 (31.3)

  

  Small cell carcinoma

133 (16.9)

  

  Large cell carcinoma

24 (3.1)

  

  Non-differentiated

49 (6.2)

  

  Others

9 (1.1)

  

  Clinical diagnosis

13 (1.6)

  

  Missing

2

  
  1. a Two-sided Chi-squared test and Mann–Whitney test where appropriate.
  2. b Pack-years for ever smokers.
  3. c List A includes occupations known to be associated with lung cancer.