1.3 million genome-wide SNPs associations with taxane IC50s in LCLs. (A and B) Genome-wide SNP association with paclitaxel (A) or docetaxel IC50 values (B). The y-axis represents -log10(p-values) for the association of each SNP with paclitaxel/docetaxel IC50 values. SNPs are plotted on the x-axis based on their chromosomal locations. A p-value of 10-4 is highlighted with a red line. (C) The number of overlapping SNPs associated with IC50s for both paclitaxel and docetaxel with p-value < 10-3.