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Table 2 Median and inter-quartile range of levels of TS and DPD protein in xenograft tumors

From: Prognostic significance of 5-fluorouracil metabolism-relating enzymes and enhanced chemosensitivity to 5-fluorouracil by 5-chloro 2,4-dihydroxy-pyridine in urothelial carcinoma

  TS (ng/mg protein) DPD (ng/mg protein)
Control 395 (386–425) 532 (511–552)
Tegafur 412 (402–423) 495 (474–535)
UFT 435 (412–455) 454*,** (431–472)
S-1 511*,**,*** (487–531) 351*,**,*** (331–382)
  1. *p < 0.05 compared with control; **p < 0.05 compared with tegafur. ***p < 0.05 compared with UFT.
  2. TS: thymidylate synthase; DPD: dihydropyrimidine dehydrogenase.
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BMC Cancer

ISSN: 1471-2407

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