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Table 7 Cox proportional hazard models (59 patients without lymph node metastasis)

From: Copy Number Amplification of the PIK3CA Gene Is Associated with Poor Prognosis in Non-lymph node metastatic Head and Neck Squamous Cell Carcinoma

Variable Crude HR 95% CI P value AHR 95% CI P value
PIK3CA amplification 2.83 1.08-7.36 0.003 3.13 1.16-8.4 0.024
Mutation (PIK3CA K-Ras) 0.73 0.09-5.6 0.77 0.83 0.1-6.78 0.86
Age 0.97 0.93-1.00 0.13 0.95 0.91-1.0 0.075
Gender 1.22 0.52-2.84 0.64 1.06 0.42-2.65 0.89
Smoking status 1.01 0.99-1.03 0.08 1.02 0.99-1.04 0.06
  1. Adjusted for age, gender, smoking status, mutation status.
  2. HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.
  3. Cox proportional hazard models were computed to determine the significance of PIK3CA amplification with adjustment for age, gender, smoking status and mutation status.