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Table 4 Crude and adjusted odds ratios (OR) and 95% confidence intervals (95% CI) for postmenopausal breast cancer risk factors among parous women

From: Postmenopausal breast cancer in Iran; risk factors and their population attributable fractions

Variable

Events

Crude OR

Adjusted OR1

Case/control

(95%CI)

(95%CI)

Parity

 Overall

455/481

  

 1 – 3

130/76

1

1

 4 – 6

227/197

0.67 (0.47 – 0.94)

0.74 (0.50 – 1.09)

 7+

98/208

0.27 (0.19 – 0.39)

0.30 (0.20 – 0.47)

 P for trend

 

< 0.001

< 0.001

Age at first childbirth

 Overall

454/481

  

 <15

41/56

0.87 (0.56 – 1.34)

0.55 (0.28 – 1.10)

 15 - 24

318/381

1

1

 ≥ 25

95/44

2.57 (1.75 – 3.79)

1.24 (0.40 – 3.80)

 P for trend

 

< 0.001

0.77

Breastfeeding (months)

 Overall

454/481

  

 Never

21/20

0.63 (0.33 – 1.20)

0.93 (0.29 – 1.86)

 1 – 94

268/162

1

1

 95 – 162

131/149

0.53 (0.39 – 0.72)

0.87 (0.27 – 2.78)

 > 162

34/150

0.13 (0.08 – 0.21)

0.32 (0.08 – 1.22)

 P for trend

 

< 0.001

0.30

Breastfeeding per child

 Overall

454/479

  

 Never

21/20

0.91 (0.47 – 1.78)

0.98 (0.71 – 1.35)

 < 12 months

125/110

1

1

 ≥ 12 months

308/349

0.77 (0.57 – 1.04)

0.92 (0.45 – 1.88)

 P for trend

 

0.20

0.68

OCP usage (months)

 Overall

454/481

  

 Never

178/236

1

1

 1 – 48

135/90

1.50 (1.15 – 1.95)

1.99 (1.03 – 3.83)

 49 – 116

73/73

1.98 (1.42 – 2.77)

2.25 (1.12 – 4.49)

 > 116

68/82

1.32 (0.90 – 1.93)

1.40 (0.66 – 2.99)

 P for trend

 

0.36

0.10

  1. 1Adjusted for all variables in the table in addition to age, age at menarche, education, BMI and family history of breast cancer.