From: Postmenopausal breast cancer in Iran; risk factors and their population attributable fractions
Parameter | Events | Crude OR (95% CI) | Adjusted OR (95%CI)1 |
---|---|---|---|
Cases/Controls | Â | Â | |
Parity | |||
 Nulliparous | 38/12 | 1 | 1 |
 1 – 3 | 130/76 | 0.50 (0.25 – 1.02) | 0.53 (0.25 – 1.15) |
 4 – 6 | 227/197 | 0.34 (0.17 – 0.67) | 0.47 (0.29 – 0.93) |
 7+ | 98/208 | 0.14 (0.07 – 0.28) | 0.23 (0.11 – 0.50) |
 P for trend |  | < 0.001 | < 0.001 |
Age at menarche (years) | |||
 < 12 | 42/25 | 1.80(1.07 – 3.02) | 1.72 (0.96 – 3.07) |
 12 – 15 | 395/425 | 1 | 1 |
 > 15 | 56/43 | 1.40 (0.91 – 2.13) | 1.11 (0.86 – 2.24) |
 P for trend |  | 0.75 | 0.09 |
Education | |||
 None | 179/292 | 1 | 1 |
 Elementary | 155/123 | 2.05 (1.51 – 2.79) | 1.33 (0.83 – 2.29) |
 High school | 108/62 | 2.84 (1.95 – 4.12) | 1.26 (0.78 – 2.03) |
 University | 51/16 | 5.19 (2.81 – 9.59) | 1.50 (0.64 – 3.48) |
 P for trend |  | < 0.001 | 0.06 |
Occupation | |||
 Housewife | 391/462 | 1 | 1 |
 Employed | 102/31 | 3.88 (2.51 – 5.99) | 2.05 (1.15 – 3.92) |
Height (cm) 2 | |||
 ≤ 151 | 143/132 | 1 | 1 |
 152 – 156 | 160/122 | 1.21(0.86 – 1.69) | 1.12 (0.77 – 1.62) |
 157 – 160 | 90/163 | 0.50(0.35 – 0.72) | 0.73 (0.49 – 1.71) |
 > 160 | 85/76 | 1.03(0.69 – 1.52) | 1.08 (0.69 – 1.66) |
 Missing | 15/0 |  |  |
 P for trend |  | 0.06 | 0.10 |
BMI (Overall) | |||
 < 18.5 | 4/14 | 0.38 (0.12 – 1.19) | 0.60 (0.17 – 2.11) |
 18.5 – 24.9 | 129/181 | 1 | 1 |
 25 – 29.9 | 208/193 | 1.43 (1.06 – 1.95) | 1.39 (1.02 – 1.94) |
 ≥ 30 | 141/119 | 1.58 (1.12 – 2.22) | 1.61 (1.18 – 2.30) |
 Missing | 15/0 |  |  |
 P for trend |  | <0.001 | 0.01 |
BMI (age <58 years) | |||
 < 18.5 | 4/5 | 0.90 (0.23 – 3.55) | - |
 18.5 – 24.9 | 78/90 | 1 | 1 |
 25 – 29.9 | 126/123 | 1.18 (0.79 – 1.74) | 1.27 (0.80 – 2.02) |
 ≥ 30 | 89/82 | 1.25(0.81 – 1.91) | 1.21 (0.73 – 1.99) |
 P for trend |  | 0.30 | 0.47 |
BMI (age ≥58 years) | |||
 < 18.5 | 0/9 | - | - |
 18.5 – 24.9 | 47/77 | 1 | 1 |
 25 – 29.9 | 82/70 | 1.91 (1.18 – 3.11) | 1.56 (0.97 – 2.65) |
 ≥ 30 | 52/37 | 2.30 (1.32 – 4.01) | 2.34 (1.33 – 4.14) |
 P for trend |  | 0.002 | 0.008 |
 P for interaction3 |  | 0.16 | 0.09 |
F.H. of breast cancer | |||
 No | 422/470 | 1 | 1 |
 Yes | 71/23 | 3.50 (2.37 – 5.17) | 2.61 (1.72 – 3.96) |
 1st relative | 43/15 | 3.19(1.73 – 5.86) | 2.13 (1.20 – 4.46) |
 2nd relative | 28/8 | 3.89(1.74 – 8.69) | 1.98 (0.96 – 5.62) |
 P for trend |  | < 0.001 | 0.003 |