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Table 3 Crude and adjusted odds ratios (OR) and 95% confidence intervals (CI) of the 493 cases and 493 controls in the study in Southern Iran

From: Postmenopausal breast cancer in Iran; risk factors and their population attributable fractions

Parameter

Events

Crude OR (95% CI)

Adjusted OR (95%CI)1

Cases/Controls

  

Parity

 Nulliparous

38/12

1

1

 1 – 3

130/76

0.50 (0.25 – 1.02)

0.53 (0.25 – 1.15)

 4 – 6

227/197

0.34 (0.17 – 0.67)

0.47 (0.29 – 0.93)

 7+

98/208

0.14 (0.07 – 0.28)

0.23 (0.11 – 0.50)

 P for trend

 

< 0.001

< 0.001

Age at menarche (years)

 < 12

42/25

1.80(1.07 – 3.02)

1.72 (0.96 – 3.07)

 12 – 15

395/425

1

1

 > 15

56/43

1.40 (0.91 – 2.13)

1.11 (0.86 – 2.24)

 P for trend

 

0.75

0.09

Education

 None

179/292

1

1

 Elementary

155/123

2.05 (1.51 – 2.79)

1.33 (0.83 – 2.29)

 High school

108/62

2.84 (1.95 – 4.12)

1.26 (0.78 – 2.03)

 University

51/16

5.19 (2.81 – 9.59)

1.50 (0.64 – 3.48)

 P for trend

 

< 0.001

0.06

Occupation

 Housewife

391/462

1

1

 Employed

102/31

3.88 (2.51 – 5.99)

2.05 (1.15 – 3.92)

Height (cm) 2

 ≤ 151

143/132

1

1

 152 – 156

160/122

1.21(0.86 – 1.69)

1.12 (0.77 – 1.62)

 157 – 160

90/163

0.50(0.35 – 0.72)

0.73 (0.49 – 1.71)

 > 160

85/76

1.03(0.69 – 1.52)

1.08 (0.69 – 1.66)

 Missing

15/0

  

 P for trend

 

0.06

0.10

BMI (Overall)

 < 18.5

4/14

0.38 (0.12 – 1.19)

0.60 (0.17 – 2.11)

 18.5 – 24.9

129/181

1

1

 25 – 29.9

208/193

1.43 (1.06 – 1.95)

1.39 (1.02 – 1.94)

 ≥ 30

141/119

1.58 (1.12 – 2.22)

1.61 (1.18 – 2.30)

 Missing

15/0

  

 P for trend

 

<0.001

0.01

BMI (age <58 years)

 < 18.5

4/5

0.90 (0.23 – 3.55)

-

 18.5 – 24.9

78/90

1

1

 25 – 29.9

126/123

1.18 (0.79 – 1.74)

1.27 (0.80 – 2.02)

 ≥ 30

89/82

1.25(0.81 – 1.91)

1.21 (0.73 – 1.99)

 P for trend

 

0.30

0.47

BMI (age ≥58 years)

 < 18.5

0/9

-

-

 18.5 – 24.9

47/77

1

1

 25 – 29.9

82/70

1.91 (1.18 – 3.11)

1.56 (0.97 – 2.65)

 ≥ 30

52/37

2.30 (1.32 – 4.01)

2.34 (1.33 – 4.14)

 P for trend

 

0.002

0.008

 P for interaction3

 

0.16

0.09

F.H. of breast cancer

 No

422/470

1

1

 Yes

71/23

3.50 (2.37 – 5.17)

2.61 (1.72 – 3.96)

 1st relative

43/15

3.19(1.73 – 5.86)

2.13 (1.20 – 4.46)

 2nd relative

28/8

3.89(1.74 – 8.69)

1.98 (0.96 – 5.62)

 P for trend

 

< 0.001

0.003

  1. (Abbreviation F.H.: Family History).
  2. 1Adjusted for all variables in the table in addition to age.
  3. 2Height was categorized based on approximate quartile values of the control population.
  4. 3Multiplicative interaction between BMI and age.