The effect of metformin and thiazolidinedione use on lung cancer in diabetics

BMC Cancer

Table 2 Association between diabetic medication use and a diagnosis of lung cancer

		Lung cancer	Control 1	Control 2	P-value
Metformin and/or TZD	Any use	41.2	61.0	93.9	<0.001
	>24 months	24.6	55.5	75.1	<0.001
Metformin alone	Any use	25.0	30.3	49.5	<0.001
TZD alone	Any use	6.5	10.5	9.9	<0.001
Insulin use		26.8		33.9	0.014
Sulfonylurea use		39.1		42.0	0.34

All numbers expressed as % of subjects taking the drugs listed in each category. Control 1 = started the defined medication prior to the diagnosis of lung cancer in the matched case, Control 2 = started the defined medication either prior to or after the diagnosis of lung cancer in the matched case.

ISSN: 1471-2407