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Figure 3 | BMC Cancer

Figure 3

From: SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

Figure 3

Western blot showing loss of SDHA expression in the young adult GIST carrying a germline SDHA exon 2 mutation p.Arg31X (GIST318, primary gastric tumor; GIST353, liver metastasis), as well as in the young adult GIST carrying a somatic SDHA exon 2 mutation (GIST118, peritoneal metastasis). Remaining WT GIST (GIST#289, 491, 507, 517) lacking SDHA mutations showed preserved SDHA protein expression.

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