Skip to main content

Table 2 Clinical, pathological and genomic features vs recurrent disease (N = 37)

From: Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease

 

N% Recurrent disease (N = 13) (35%)

N% Non-recurrent disease (N = 24) (64.9%)

P value

Age(mean)

64.0 years

61.8 years

p = 0.612 (t-test)

Tumor grade

G1 + G2

8.(62)

14 (58)

 

G3

5 (38)

10 (42)

p = 0.849 (chi-2)

FIGO stage

   

IA-IC

8 (61)

23 (96)

 

II

5 (42)

1 (4)

p = 0.007 (chi-2)

Staging

adequate

1 (8)

6 (25)

 

not adequate

12 (92)

18 (75)

p = 0.199 (chi-2)

LOH detected

at19q (51-56Mbp)

8 (62)

3 (12)

 

No. LOH at 19q

5 (38)

21 (88)

p = 0.002 (chi 2)

(51-56Mbp) detected

   

TP53 status

positive

8 (62)

4 (17)

 

negative

5 (38)

20 (83)

p = 0.005 (chi-2)