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Table 2 Expression of detectable levels (abundance ≥ 50) of MPL , EPOR , ERBB2, and IGF1R mRNA in normal tissue and tumor samples by qRT-PCR

From: Low or undetectable TPO receptor expression in malignant tissue and cell lines derived from breast, lung, and ovarian tumors

 

Breast normal N = 7 n (%)

Breast tumor N = 40 n (%)

Lung normal N = 8 n (%)

Lung tumor N = 40 n (%)

Ovarian normal N = 7 n (%)

Ovarian tumor N = 41 n (%)

MPL

1 (14)

1 (3)

1 (13)

1 (3)

3 (43)

3 (7)

EPOR

7 (100)

32 (80)

8 (100)

28 (70)

7 (100)

41 (100)

ERBB2

4 (57)

33 (83)

8 (100)

22 (55)

7 (100)

39 (95)

IGF1R

2 (29)

15 (38)

1 (13)

2 (5)

0 (0)

7 (17)

  1. Quantitative reverse transcription-polymerase chain reaction was used to measure abundance of these genes. Data are represented as number of samples with detectable expression and percent of the samples in parenthesis.