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Figure 8 | BMC Cancer

Figure 8

From: HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast

Figure 8

A and B: Hematoxylin and Eosin staining of formalin fixed paraffin embedded MCF7 3-D spheroids . (A, bar 40 microns) The spheroids had almost the same morphology and diameter of the micropapillae of the carcinoma in breast biopsy from a patient with IMPC (B, bar 40 microns). C and D: Immunohistochemical staining for MUC1 in formalin fixed paraffin embedded MCF7 3-D spheroids (C, bar 10 microns) and biopsy from a patient with IMPC of the breast (D, bar 10 microns). E and F: Immunohistochemical staining for HIF1-α in formalin fixed paraffin embedded MCF7 3-D spheroids (E, bar 12 microns) and biopsy from a patient with IMPC of the breast (F, bar 12 microns). The figures are representative of three similar experiments.

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BMC Cancer

ISSN: 1471-2407

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