Table 5 Comparison of Diagnostic Results of NAB alone and NAB combined with Tumor Markers according to tumor stage
Diagnostic Method | Sensitivity (%) | Specificity (%) | Accuracy (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|
Early Stage (Stage 1 and 2, n=55) | |||||
NAB alone | 75.9 | 100 | 88.1 | 100 | 80.9 |
NAB+Serum Tumor marker | |||||
CYFRA (3.3) | 77.8 | 81.8 | 79.8 | 80.8 | 78.9 |
CEA (5) | 75.9 | 90.9 | 83.5 | 89.1 | 79.4 |
SCC (2) | 75.9 | 92.7 | 84.4 | 91.1 | 79.7 |
NAB+Cytological Tumor marker | |||||
CYFRA (15.7) | 94.4 | 98.2 | 96.3 | 98.1 | 94.7 |
CEA (0.6) | 87 | 92.7 | 89.9 | 92.2 | 87.9 |
SCC (0.86) | 87 | 70.9 | 78.9 | 74.6 | 84.8 |
Advanced Stage (Stage 3 and 4, n=84) | |||||
NAB alone | 88.1 | 100 | 92.8 | 100 | 84.6 |
NAB+Serum Tumor marker | |||||
CYFRA (3.3) | 90.5 | 81.8 | 87.1 | 88.4 | 84.9 |
CEA (5) | 92.9 | 90.9 | 92.1 | 94 | 89.3 |
SCC (2) | 89.3 | 92.7 | 90.6 | 94.9 | 85 |
NAB+Cytological Tumor marker | |||||
CYFRA (15.7) | 95.2 | 98.2 | 96.4 | 98.8 | 93.1 |
CEA (0.6) | 95.2 | 92.7 | 94.2 | 95.2 | 92.7 |
SCC (0.86) | 94 | 70.9 | 84.9 | 83.2 | 88.6 |