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Table 2 Comparisons of physical and psychosocial symptom burden between chemotherapy lines.

From: Quality of life across chemotherapy lines in patients with cancers of the pancreas and biliary tract

EORTC QLQ-C30 (0) (1) (2) (3) p
  Adjuvant CT 1st pall. CT 2nd pall. CT 3rd+pall. CT  
Physical Functioning 73.52,3 71.02 65.60,1 62.80 0.036
Role Functioning 58.0 58.4 53.1 53.1 0.438
Social Functioning 79.0 74.4 74.8 69.6 0.145
Emotional Functioning 84.41,2,3 73.80 71.70 71.10 <0.001
Cognitive Functioning 92.01,2 86.90 85.10 89.5 0.034
Global QOL 60.62 59.72 51.701 53.9 0.002
Fatigue 39.12,3 41.52,3 50.00,1 53.10,1 0.004
Pain 14.11,2,3 21.80,2 28.80,1 23.60 <0.001
Nausea/Vomiting 7.6 13.2 12.2 11.0 0.128
Dyspnoea 10.82,3 14.52,3 23.60,1,3 31.40,1,2 <0.001
Appetite Loss 25.6 28.6 32.8 38.8 0.194
Sleeping Disturbances 18.71,2,3 32.50 31.30 29.20 0.001
Constipation 19.4 17.9 12.0 14.3 0.173
Diarrhoea 7.52,3 12.53 16.60 21.30,1 0.002
Financial Impact 10.8 11.3 12.0 12.8 0.946
Taste Alterations 12.72,3 17.8 22.00 22.60 0.046
  1. Superscript numbers indicate significant differences to other groups in pairwise comparisons.