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Table 4 Relative intensities of metabolites at pre- and post-treatment

From: Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy

   Pre-treatment (mean ± SE) Post-treatment (mean ± SE)
Metabolites ppm Survivors Non-survivors p-value Survivors Non-survivors p-value
Lactate 4.08-4.13 185.8 ± 11.4 164.6 ± 13.8 0.534 196.2 ± 12.7 250.6 ± 26.0 0.089
Glycine 3.54-3.56 115.0 ± 6.4 120.8 ± 11.0 0.542 91.2 ± 4.1 111.4 ± 8.4 0.033*
GPC 3.22-3.24 167.3 ± 12.4 170.1 ± 23.9 0.949 115.6 ± 6.7 153.9 ± 24.1 0.144
PC 3.21-3.22 247.9 ± 17.0 285.4 ± 34.9 0.338 158.0 ± 16.1 205.5 ± 28.1 0.105
Cho 3.20-3.21 95.4 ± 3.9 108.7 ± 8.3 0.225 79.5 ± 3.7 85.9 ± 6.2 0.276
tCho 3.20-3.24 498.3 ± 26.4 551.3 ± 46.8 0.253 344.9 ± 22.3 434.6 ± 44.6 0.075
Taurine 3.40-3.43 242.6 ± 9.6 222.8 ± 12.4 0.393 248.0 ± 8.1 222.3 ± 9.3 0.144
β-Glucose 4.61-4.64 48.4 ± 3.3 49.3 ± 6.0 1.000 63.6 ± 4.3 53.5 ± 6.6 0.172
  1. The values of relative intensities are integrated peak areas from spectra normalized to equal total areas. Wilcoxon rank sum tests were used for statistical analyses. *p < 0.05, ** p < 0.01