Table 1 Descriptive characteristics of adenoma cases and adenoma-free controls
From: Elevated C-peptide and insulin predict increased risk of colorectal adenomas in normal mucosa
Variable | Cases (N = 190) | Controls (N = 488) | p-value |
|---|---|---|---|
Mean Age in Years (SE) | 56.8 (0.7) | 55.7 (0.5) | 0.19 |
White (%) | 156 (82) | 383 (78) | 0.34 |
Male (%) | 112 (59) | 188 (39) | 0.0001 |
Mean Body Mass Index (SE) | 28.3 (0.4) | 27.1 (0.3) | 0.02 |
Family History of CRC (%) | 28 (17) | 60 (14) | 0.37 |
Mean Dietary Fat (g/day) (SE) | 70.8 (2.7) | 68.6 (1.5) | 0.47 |
Mean Alcohol1 (SE) | 12.6 (1.7) | 8.2 (0.7) | 0.02 |
Mean Waist/hip Ratio (SE) | 0.930 (0.008) | 0.886 (0.007) | 0.0001 |
Smokers (%) | 29 (17) | 49 (11) | 0.06 |
Mean Monthly NSAID Use in Past 5 Years (SE) | 12.9 (2.0) | 12.7 (1.4) | 0.94 |
Mean Total Daily Calcium (mg) (SE) | 744 (28) | 785 (18) | 0.23 |
Mean Red Meat (svgs/day) (SE) | 1.73 (0.11) | 1.47 (0.06) | 0.03 |
Apoptosis (Morphology)2 | 3.33 (0.10) | 3.76 (0.06) | 0.0003 |
C-peptide (mean, se) | 1.86 (0.10) | 1.61 (0.08) | 0.05 |
IGFBP-1 (mean, se) | 21.3 (1.60) | 24.1 (1.02) | 0.13 |
Insulin (mean, se) | 10.5 (0.8) | 8.1 (0.5) | 0.008 |
Number of Adenomas (mean, se) | 1.58 (0.08) | - | - |
Adenoma size (mean, se)3 | 6.21 (0.45) | - | Â |