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Figure 4 | BMC Cancer

Figure 4

From: Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization

Figure 4

Doxorubicin and doxorubicinol cytotoxicity in MCF-7 CC12 and MCF-7 DOX2-12 cells upon treatment with or without 5β-cholanic acid . MCF-7CC12 and MCF-7DOX2-12 cells were assessed for their sensitivity to doxorubicin and doxorubicinol in the presence or absence of the AKR1B10, AKR1C2, and AKR1C3 inhibitor 5β-cholanic acid using a clonogenic assay.

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