Figure 4From: SNP microarray analyses reveal copy number alterations and progressive genome reorganization during tumor development in SVT/t driven mice breast cancer Segmentation differences in developmental stages. Fragmentation patterns which have frequently been observed are shown here; a section of chromosome 5 (55Mb to 85Mb) is taken as an example. Comparing Transgenic1 and Tumor1, one can find not only an increase in copy number alteration, but also a progressive fragmentation of previously found segments. These fragmentation patterns can be found in all WAP-SVT/t derived samples. The results for Normal2, Transgenic2 and Tumor2 were comparable (data not shown).Back to article page