Figure 3

Proteasome inhibition effects on kinase levels in geldanamycin-treated cells. Relative quantification of kinases identified from Hs68 and SW480 cells treated with geldanamycin for 24 h with or without MG132 addition following enrichment on Kinobeads (from two independent experiments). Fold change refers to the ratio between geldanamycin + MG132-treated and geldanamycin-treated cells. Kinases are highly significantly increased (dark orange or blue) when fold change is > 1.2 and p-value < 0.01. FC - fold change.