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Table 3 Expression of angiogenic factors in gastrointestinal cancer cell lines

From: Biomarkers for antitumor activity of bevacizumab in gastric cancer models

Cell line Sensitivity to bevacizumab VEGF PlGF IL-8 bFGF
COL-16-JCK + 4430 ± 991 < 15.6 360 ± 171 268 ± 75.3
SC-08-JCK + 2330 ± 402 < 15.6 < 31.3 145 ± 25.9
GXF97 + 1950 ± 753 < 15.6 362 ± 134 107 ± 63.6
MKN-45 + 1560 ± 310 < 15.6 65.9 ± 9.38 183 ± 43.0
CXF280 + 1480 ± 290 < 15.6 < 31.3 77.6 ± 16.5
SC-09-JCK + 1020 ± 163 < 15.6 165 ± 60.3 151 ± 13.3
4-1ST + 706 ± 106 < 15.6 < 31.3 87.7 ± 5.47
MKN-28 + 577 ± 285 16.4 ± 8.22 < 31.3 200 ± 27.8
SC-10-JCK - 760 ± 80.2 < 15.6 198 ± 96.5 231 ± 105
NCI-N87 - 171 ± 52.5 < 15.6 34.4 ± 10.8 1090 ± 328
SCH - < 31.3 1210 ± 205 < 31.3 38.4 ± 18.6
  1. Mean ± SD (pg/mg protein)
  2. The expression of human VEGF, PlGF, IL-8 and bFGF in tumor tissues were examined by ELISA