Expression of human bFGF protein in tumor tissues of gastric and colorectal cancer xenograft models. (A) The level of human bFGF, PlGF, and IL-8 proteins in tumor tissues sensitive (9 models) or insensitive (3 models) to bevacizumab was quantified by ELISA (n = 4). Open circle means less than the detection limit of ELISAs. The averages were shown as bars and numeric values. (B) The ratio of VEGF to bFGF was compared between the two groups. *: P < 0.05 vs. sensitive group by Wilcoxon test.