Elevated levels of serum amyloid A indicate poor prognosis in patients with esophageal squamous cell carcinoma

BMC Cancer

Table 1 Relationship between the SAA concentration and the clinicopathological variables in 167 patients with esophageal carcinoma

Variables	Cases	SAA(mg/L)	Significance	SAA	SAA	Significance
	(n)	(Mean±SD)	(P)*	<8.0 mg/L	≥8.0 mg/L	(P)*
Gender
Male	129	14.89±15.72	0.084	54	75	0.126
Female	38	10.62±13.01		21	17
Age (y)
<60	83	12.57±13.58	0.083	43	40	0.086
≥60	84	15.41±16.74		32	52
Location
Up	49	15.32±17.36	0.381	23	26	0.361
Middle	88	12.61±14.51		43	45
Low	30	15.80±13.81		10	20
Tumor diameter
<50 mm	102	8.02±9.30	<0.001	66	36	<0.001
≥50 mm	65	23.15±17.93		10	55
Histological differentiation
Well	53	5.91±3.59	0.015	35	18	<0.001
Moderate	73	16.76±8.88		27	46
Poor	21	17.42±17.22		4	17
pT classification
T1	11	5.06±4.79	<0.001	7	4	<0.001
T2	23	7.17±6.81		16	7
T3	93	12.96±13.59		42	51
T4	40	22.08±20.02		6	34
pN classification
No	72	9.99±12.88	0.006	43	29	<0.001
Yes	95	17.03±16.38		29	66
pMetastasis
No	132	10.21±10.97	<0.001	68	64	<0.001
Yes	35	27.92±20.42		4	31
Stage
I	17	5.82±4.81	<0.001	13	4	<0.001
IIa	25	6.90±13.76		16	9
IIb	25	8.82±7.88		15	10
III	61	11.68±9.60		26	35
IV	39	27.73±20.58		3	36

ISSN: 1471-2407