Table 2 The most recurrent chromosomal aberrations detected by BAC CGH-array in a panel of 28 SPRD-CU3 DMBA-induced mammary tumors
RNO | Position (Mb) in the rat genome | Rat position | Homologous position in human | Frequency |
|---|---|---|---|---|
Loss | Â | Â | Â | Â |
5q | ~108 | 5q32 | 9p21 | 20 (71%) |
6q | ~60-66 | 6q21 | 14q12, 7q22 | 15 (53%) |
4q | ~38-43 | 4q21 | 7p21, 7p31 | 6 (21%) |
20q | ~49-telomere | 20q13 | 6q21 | 4 (41%) |
Gain | Â | Â | Â | Â |
12q | ~15 | 12q11 | 7p22 | 15 (53%) |
20q | ~44 | 20q12 | 6q21 | 14 (50%) |
20p | ~15 | 20p11 | 10q21 | 12 (43%) |
20p | ~3 | 20p12 | UN | 11 (39%) |
10q | ~54 | 10q24 | 17p13 | 11 (39%) |
10q | ~13 | 10q12 | 16p13 | 8 (28%) |
12q | ~44 | 12q16 | 12q24 | 5 (18%) |