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Table 2 Correlation of EMT-associated protein markers and TGF-β with CD68+ macrophage tumor infiltration

From: Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

Proteins   CD68+ intratumoral TAMs Grade
   Evaluation 1 Evaluation 2 1-3
E-cadherin membrane SC -0.001 -0.073 -0.104
  p 0.035 0.111 0.021
β-Catenin membrane SC -0.174 -0.175 -0.190
  p 0.001 0.001 0.001
β-Catenin cytoplasm SC 0.223 0.231 0.163
  p 0.001 0.001 0.001
Vimentin cytoplasm SC 0.225 0.485 0.178
  p 0.001 0.001 0.001
Periostin cytoplasm SC 0.177 0.215 0.112
  p 0.001 0.001 0.008
TGF-β intraepithelial SC 0.230 0.184 0.254
  p 0.001 0.001 0.001
  1. p-values and Spearman correlation values (SC) are indicated. Statistical analysis was done with SPSS 16.0. Tumors, n = 491