Skip to main content

Table 2 Correlation of EMT-associated protein markers and TGF-β with CD68+ macrophage tumor infiltration

From: Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

Proteins

 

CD68+ intratumoral TAMs

Grade

  

Evaluation 1 Evaluation 2

1-3

E-cadherin membrane

SC

-0.001

-0.073

-0.104

 

p

0.035

0.111

0.021

β-Catenin membrane

SC

-0.174

-0.175

-0.190

 

p

≤ 0.001

≤ 0.001

≤ 0.001

β-Catenin cytoplasm

SC

0.223

0.231

0.163

 

p

≤ 0.001

≤ 0.001

≤ 0.001

Vimentin cytoplasm

SC

0.225

0.485

0.178

 

p

≤ 0.001

≤ 0.001

≤ 0.001

Periostin cytoplasm

SC

0.177

0.215

0.112

 

p

≤ 0.001

≤ 0.001

0.008

TGF-β intraepithelial

SC

0.230

0.184

0.254

 

p

≤ 0.001

≤ 0.001

≤ 0.001

  1. p-values and Spearman correlation values (SC) are indicated. Statistical analysis was done with SPSS 16.0. Tumors, n = 491
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us