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Table 2 Bivariate correlation of B, E, R, T mRNA expression in normal lung and NSCLC tissues

From: Expression of DNA repair and replication genes in non-small cell lung cancer (NSCLC): a role for thymidylate synthetase (TYMS)

   ERCC1 RRM1 TYMS
normal lung, n = 40
BRCA1 r 0.921 0.891 0.180
  p <0.001 <0.001 0.273
ERCC1 r 1 0.933 0.244
  p   <0.001 0.135
RRM1 r   1 0.371
  p    0.020
matched NSCLC,n = 35
BRCA1 r 0.919 0.858 0.560
  p <0.001 <0.001 <0.001
ERCC1 r 1 0.904 0.564
  p   <0.001 <0.001
RRM1 r   1 0.628
  p    <0.001
all NCLC,n = 276
BRCA1 r 0.522 0.383 0.511
  p <0.001 <0.001 <0.001
ERCC1 r 1 0.625 0.350
  p   <0.001 <0.001
RRM1 r   1 0.358
  p    <0.001
  1. Notes to Table 2: r = Spearman's Correlation Coefficient; p = Significance (2-tailed).