Skip to main content

Table 2 Univariate and multivariate Cox regression analysis of overall survival among patients AM-RCC who underwent nephrectomy of any kind (n = 81)

From: C-reactive protein in patients with advanced metastatic renal cell carcinoma: Usefulness in identifying patients most likely to benefit from initial nephrectomy

Parameter

Univariate

Multivariate

 

n

P

HR

95% CI

P

HR

95% CI

Age, yr

       

<62.0

39

 

1.00

  

1.00

 

≥62.0

42

0.026

1.87

1.08−3.26

0.177

1.51

0.083−2.76

Sex

       

Female

25

 

1.00

  

X

 

Male

56

0.840

0.94

0.53-1.68

   

ECOG PS

       

0

44

1.00

   

1.00

 

1

32

0.001

2.54

1.45-4.34

0.012

2.22

1.19-4.16

≥2

5

0.000

7.89

2.56-24.3

0.022

4.18

1.23-14.3

Hb

       

≥Lower normal limit

45

 

1.00

  

1.00

 

<Lower normal limit

36

0.047

1.72

1.01-2.92

0.862

1.06

0.58-1.93

LDH

       

≦Normal limit × 1.5

51

 

1.00

  

x

 

>Normal limit × 1.5

30

0.567

1.17

0.69-2.00

   

ALP

       

≦Normal limit × 1.5

78

 

1.00

  

1.00

 

>Normal limit × 1.5

3

0.026

3.92

1.18-13.0

0.510

0.60

0.13-2.76

Corrected Ca, mg/dL

       

<10.0

50

 

1.00

  

x

 

≥10.0

31

0.404

0.79

0.45-138

   

Max. tumor diameter, cm

       

<8.0

41

 

1.00

  

x

 

≥8.0

40

0.381

0.78

0.45-1.35

   

No. of metastatic organ sites

       

0,1

35

 

1.00

    

≥2

46

0.054

1.72

0.99-2.99

0.011

2.33

1.21-4.48

CRP, mg/L

       

≦18.0

49

 

1.00

  

1.00

 

>18.0, <67.

20

0.057

1.86

0.98-3.54

0.036

2.06

1.05-4.05

0 ≥ 67.0

12

0.000

6.66

3.16-14.01

0.001

5.85

2.07-16.56

  1. *X, excluded from the multivariate analysis.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us