Parameter
|
Univariate
|
Multivariate
|
---|
|
n
|
P
|
HR
|
95% CI
|
P
|
HR
|
95% CI
|
---|
Age, yr
| | | | | | | |
<62.0
|
39
| |
1.00
| | |
1.00
| |
≥62.0
|
42
|
0.026
|
1.87
|
1.08−3.26
|
0.177
|
1.51
|
0.083−2.76
|
Sex
| | | | | | | |
Female
|
25
| |
1.00
| | |
X
| |
Male
|
56
|
0.840
|
0.94
|
0.53-1.68
| | | |
ECOG PS
| | | | | | | |
0
|
44
|
1.00
| | | |
1.00
| |
1
|
32
|
0.001
|
2.54
|
1.45-4.34
|
0.012
|
2.22
|
1.19-4.16
|
≥2
|
5
|
0.000
|
7.89
|
2.56-24.3
|
0.022
|
4.18
|
1.23-14.3
|
Hb
| | | | | | | |
≥Lower normal limit
|
45
| |
1.00
| | |
1.00
| |
<Lower normal limit
|
36
|
0.047
|
1.72
|
1.01-2.92
|
0.862
|
1.06
|
0.58-1.93
|
LDH
| | | | | | | |
≦Normal limit × 1.5 |
51
| |
1.00
| | |
x
| |
>Normal limit × 1.5
|
30
|
0.567
|
1.17
|
0.69-2.00
| | | |
ALP
| | | | | | | |
≦Normal limit × 1.5 |
78
| |
1.00
| | |
1.00
| |
>Normal limit × 1.5
|
3
|
0.026
|
3.92
|
1.18-13.0
|
0.510
|
0.60
|
0.13-2.76
|
Corrected Ca, mg/dL
| | | | | | | |
<10.0
|
50
| |
1.00
| | |
x
| |
≥10.0
|
31
|
0.404
|
0.79
|
0.45-138
| | | |
Max. tumor diameter, cm
| | | | | | | |
<8.0
|
41
| |
1.00
| | |
x
| |
≥8.0
|
40
|
0.381
|
0.78
|
0.45-1.35
| | | |
No. of metastatic organ sites
| | | | | | | |
0,1
|
35
| |
1.00
| | | | |
≥2
|
46
|
0.054
|
1.72
|
0.99-2.99
|
0.011
|
2.33
|
1.21-4.48
|
CRP, mg/L
| | | | | | | |
≦18.0 |
49
| |
1.00
| | |
1.00
| |
>18.0, <67.
|
20
|
0.057
|
1.86
|
0.98-3.54
|
0.036
|
2.06
|
1.05-4.05
|
0 ≥ 67.0
|
12
|
0.000
|
6.66
|
3.16-14.01
|
0.001
|
5.85
|
2.07-16.56
|
- *X, excluded from the multivariate analysis.