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Table 1 Clinicopathologic characteristics of patients with advanced metastatic RCC treated with any kind of nephrectomy and no nephrectomy

From: C-reactive protein in patients with advanced metastatic renal cell carcinoma: Usefulness in identifying patients most likely to benefit from initial nephrectomy

Characteristic Any nephrectomy No nephrectomy P
Number of patients (%) 129 (71.3) 52 (28.7)  
Age, yr    
Median 62 67.5 0.006*
Range 30–81 36–86  
Sex    
Female 33 15 0.780**
Male 96 37  
PS    
0 64 14 <0.001*
1 57 20  
≥2 8 18  
No. of metastatic organ sites
0(T4N0M0) 6 1 0.295*
1 82 22  
2 17 6  
≥3 24 23  
Metastatic area    
Lung 68 30 0.657**
Bone 46 13 0.227**
Lymph node 31 19 0.089**
Liver 4 7 0.008**
CNS 4 4 0.174**
Others 17 7 0.856*
Median 8.00 9.25 0.008*
Range 2.50– 24.0  
Histopathology    
Clear cell 109 17  
Papillary 4 0  
Chromophobe 1 0  
Collecting-duct 4 0  
Sarcomatoid change 3 5  
Others or not determined 8 30  
Tumor grading (Fuhrman)    0.205*
G1 4 1  
G2 43 4  
G3 57 7  
G4 20 6  
X   5 34
  1. *Mann-Whitney U test; **Chi-square test.