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Table 3 Associations between immunohistochemical expression, histology and tumor size

From: Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer

   Histological subtype Tumor size
   ADC (n = 123) SCC (n = 49) LCC (n = 24) p value* ≤ 3.0 cm (n = 1 9) ≥ 3.1 cm (n = 87) p value*
S100A4c negative/weak 34% 57% 58%   36% 51%  
  moderate 37% 37% 38%   38% 36%  
  strong 29% 6% 4% 0.001 26% 13% 0.01
S100A4n negative 13% 33% 29%   18% 22%  
  weak 32% 34% 38%   29% 40%  
  moderate 26% 27% 29%   27% 25%  
  strong 29% 6% 4% 0.001 26% 13% 0.04
Ephrin-A1 negative 11% 29% 4%   15% 14%  
  moderate 71% 65% 92%   70% 75%  
  strong 18% 6% 4% 0.004 15% 11% 0.79
Osteopontin negative 23% 21% 25%   26% 20%  
  moderate 67% 61% 66%   62% 69%  
  strong 10% 18% 9% 0.61 12% 11% 0.54
  1. * p value calculated by Fisher´s exact test or linear by linear association test as appropriate.