Table 3 Associations between immunohistochemical expression, histology and tumor size
From: Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer
| Â | Â | Histological subtype | Tumor size | |||||
|---|---|---|---|---|---|---|---|---|
|  |  | ADC (n = 123) | SCC (n = 49) | LCC (n = 24) | p value* | ≤ 3.0 cm (n = 1 9) | ≥ 3.1 cm (n = 87) | p value* |
S100A4c | negative/weak | 34% | 57% | 58% | Â | 36% | 51% | Â |
| Â | moderate | 37% | 37% | 38% | Â | 38% | 36% | Â |
| Â | strong | 29% | 6% | 4% | 0.001 | 26% | 13% | 0.01 |
S100A4n | negative | 13% | 33% | 29% | Â | 18% | 22% | Â |
| Â | weak | 32% | 34% | 38% | Â | 29% | 40% | Â |
| Â | moderate | 26% | 27% | 29% | Â | 27% | 25% | Â |
| Â | strong | 29% | 6% | 4% | 0.001 | 26% | 13% | 0.04 |
Ephrin-A1 | negative | 11% | 29% | 4% | Â | 15% | 14% | Â |
| Â | moderate | 71% | 65% | 92% | Â | 70% | 75% | Â |
| Â | strong | 18% | 6% | 4% | 0.004 | 15% | 11% | 0.79 |
Osteopontin | negative | 23% | 21% | 25% | Â | 26% | 20% | Â |
| Â | moderate | 67% | 61% | 66% | Â | 62% | 69% | Â |
| Â | strong | 10% | 18% | 9% | 0.61 | 12% | 11% | 0.54 |