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Table 3 ALDH7A1 immunohistochemical staining according to diagnosis and histological characteristics of the epithelial and stromal components of ovarian samples

From: Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures

Characteristics

n a

epithelial

stromal

  

score b

P c

C.I. d

score b

P c

Diagnosis

      

healthy

5

0.64 ± 0.47

0.005*

reference

1.70 ± 0.45

0.54

benign

4

2.63 ± 2.29

 

(-2.2, 6.2)

3.75 ± 0.50

 

borderline

3

4.58 ± 1.44

 

(-0.6, 8.5)

3.00 ± 1.00

 

invasive

40

5.36 ± 2.77

 

(1.8, 7.7)**

3.27 ± 2.67

 

Histology

      

serous

18

4.57 ± 3.09

0.34

 

2.87 ± 2.53

0.08

mucinous

8

6.44 ± 2.46

  

5.43 ± 1.86

 

endometrioid

8

5.88 ± 2.58

  

1.70 ± 1.75

 

clear cell

5

6.20 ± 1.79

  

3.25 ± 4.03

 
  1. a Number of cases.
  2. b Immunohistochemistry staining score expressed as mean ± SD.
  3. c P-value, ANOVA test of equal means among the four groups (* equal population variances assumption did not meet, corresponding p-value using Kruskal-Wallis test for equal medians was displayed).
  4. d Two-sided 95% confidence interval (C.I.) for the difference in means, Dunnett’s post-hoc test compared to value in healthy (in Diagnosis group) or clear cell (in Histology group) as the “reference” group. Dunnett’s test was performed only when the ANOVA or Kruskal-Wallis result was significant (p < 0.05).
  5. ** Significant based on Dunnett’s test (family error rate set to 0.05).
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BMC Cancer

ISSN: 1471-2407

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