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Table 2 ALDH3A2 immunohistochemical staining according to diagnosis and histological characteristics of the epithelial and stromal components of ovarian samples

From: Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures

Characteristics

n a

epithelial

stromal

  

score b

P c

C.I. d

score b

P c

Diagnosis

      

healthy

5

0.94 ± 0.38

0.003*

reference

1.90 ± 0.74

0.1*

benign

4

3.81 ± 1.84

 

(−1.0, 6.7)

2.25 ± 1.50

 

borderline

3

4.42 ± 0.63

 

(−0.7, 7.7)

1.83 ± 2.02

 

invasive

35

5.59 ± 2.60

 

(1.9, 7.4)**

1.00 ± 0.88

 

Histology

      

serous

17

5.44 ± 2.86

0.31

 

1.09 ± 0.87

0.74

mucinous

6

5.75 ± 1.17

  

0.92 ± 1.16

 

endometrioid

5

7.50 ± 2.60

  

0.65 ± 0.78

 

clear cell

6

4.54 ± 2.75

  

1.21 ± 0.87

 
  1. a Number of cases.
  2. b Immunohistochemistry staining score expressed as mean ± SD.
  3. c P-value, ANOVA test of equal means among the four groups (* equal population variances assumption did not meet, corresponding p-value using Kruskal-Wallis test for equal medians was displayed).
  4. d Two-sided 95% confidence interval (C.I.) for the difference in means, Dunnett’s post-hoc test compared to value in healthy (in Diagnosis group) or clear cell (in Histology group) as the “reference” group. Dunnett’s test was performed only when the ANOVA or Kruskal-Wallis result was significant (p < 0.05).
  5. ** Significant based on Dunnett’s test (family error rate set to 0.05).
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BMC Cancer

ISSN: 1471-2407

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