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Table 1 Sensitivity, specificity, PPV, and NPV of bone scan in 288 patients with esophageal squamous cell carcinoma

From: Is there a role of whole-body bone scan in patients with esophageal squamous cell carcinoma

7thAJCC Stage Bone metastasis Abnormal bone scan finding Sensitivity Specificity PPV NPV
All (n = 288) 25 46 80.0% (20/25) 90.1% (237/263) 43.5% (20/46) 97.9% (237/242)
Stage I (n = 23) 0 2 -(0/0) 91.3% (21/23) 0% (0/2) 100.0% (21/21)
Stage II (n = 69) 4 10 75.0% (3/4) 89.2% (58/65) 30.0% (3/10) 98.3% (58/59)
Stage III (n = 165) 13 24 76.9% (10/13) 90.8% (138/152) 41.7% (10/24) 97.9% (138/141)
Stage IV (n = 31) 8 10 87.5% (7/8) 87.0% (20/23) 70.0% (7/10) 95.2% (20/21)
  1. PPV, positive predictive value; NPV, negative predictive value.