From: Is there a role of whole-body bone scan in patients with esophageal squamous cell carcinoma
7thAJCC Stage | Bone metastasis | Abnormal bone scan finding | Sensitivity | Specificity | PPV | NPV |
---|---|---|---|---|---|---|
All (n = 288) | 25 | 46 | 80.0% (20/25) | 90.1% (237/263) | 43.5% (20/46) | 97.9% (237/242) |
Stage I (n = 23) | 0 | 2 | -(0/0) | 91.3% (21/23) | 0% (0/2) | 100.0% (21/21) |
Stage II (n = 69) | 4 | 10 | 75.0% (3/4) | 89.2% (58/65) | 30.0% (3/10) | 98.3% (58/59) |
Stage III (n = 165) | 13 | 24 | 76.9% (10/13) | 90.8% (138/152) | 41.7% (10/24) | 97.9% (138/141) |
Stage IV (n = 31) | 8 | 10 | 87.5% (7/8) | 87.0% (20/23) | 70.0% (7/10) | 95.2% (20/21) |