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Table 1 Sensitivity, specificity, PPV, and NPV of bone scan in 288 patients with esophageal squamous cell carcinoma

From: Is there a role of whole-body bone scan in patients with esophageal squamous cell carcinoma

7thAJCC Stage

Bone metastasis

Abnormal bone scan finding

Sensitivity

Specificity

PPV

NPV

All (n = 288)

25

46

80.0% (20/25)

90.1% (237/263)

43.5% (20/46)

97.9% (237/242)

Stage I (n = 23)

0

2

-(0/0)

91.3% (21/23)

0% (0/2)

100.0% (21/21)

Stage II (n = 69)

4

10

75.0% (3/4)

89.2% (58/65)

30.0% (3/10)

98.3% (58/59)

Stage III (n = 165)

13

24

76.9% (10/13)

90.8% (138/152)

41.7% (10/24)

97.9% (138/141)

Stage IV (n = 31)

8

10

87.5% (7/8)

87.0% (20/23)

70.0% (7/10)

95.2% (20/21)

  1. PPV, positive predictive value; NPV, negative predictive value.