From: Peri-operative chemotherapy in the management of resectable colorectal cancer pulmonary metastases
Details of surgical resections | Peri-operative chemotherapy | Surgery alone | Total cohort |
---|---|---|---|
n = 56 resections (38 patients) | n = 16 resections (13 patients) | n = 72 resections (51 patients) | |
Type of resection | |||
Wedge | 37 | 10 | 47 |
Segmental | 8 | 2 | 10 |
Lobectomy | 8 | 4 | 12 |
Pneumonectomy | 1 | 0 | 1 |
Not recorded | 2 | 0 | 2 |
Metastases removed | |||
Solitary | 16 | 4 | 20 |
Multiple | 38 | 12 | 50 |
Unknown | 2 | 0 | 2 |
Median size (range) | 14.5 mm (2–60) | 15 mm (4–25) | 15 mm (2–60) |
Lymph node dissection | |||
Yes | 22 | 5 | 27 |
Positive histology | 4/22 (18%) | 1/5 (20%) | 5/27 (19%) |
No | 31 | 10 | 41 |
Unknown | 3 | 1 | 4 |
Time from last dose of neoadjuvant treatment to surgery | Median days (range) | ||
Any treatment | 48.5 (14–207) | ||
Chemotherapy + | 37 (25–85) | ||
VEGF inhibitor | |||
Surgical Complications * | 3/68 (4%) | 5/16 (31%) | 8/84 (9%) |
Prolonged air leak | 3 | 0 | 3 |
Haemorrhage** | 0 | 1 | 1 |
CVA | 0 | 1 | 1 |
Cardiac Arrhythmia (fast AF) | 0 | 1 | 1 |
Small bowel ileus or obstruction | 0 | 2 | 2 |